Multiomics Solutions
Academic and Research Institutes
Unlock the Complexity of Life Sciences with Signios Bio's Multiomics Solutions
Signios Bio is your dedicated partner in advancing research and discovery. We provide cutting-edge multiomics services and bioinformatics solutions to academic and research institutions, empowering you to explore biological systems, accelerate discoveries, and drive innovation.
Why choose Signios Bio as your research partner?
Explore our full range of multiomics services
DNA Sequencing Solutions with Short or Long Reads
Whole Genome Sequencing
Study genetic variation, disease risk, and population history
Exome Sequencing
Identify protein-coding variants in disease research and diagnostics
Targeted Sequencing
Analyze specific genomic regions for mutations or biomarkers
RNA Sequencing Solutions with Short or Long Reads
Bulk RNA Sequencing
Measure gene expression changes in different conditions or tissues
scRNA Sequencing
Study gene expression in individual cells to understand cellular heterogeneity
Spatial RNA Sequencing
Map gene expression within tissue sections to study spatial organization
Epigenomic Sequencing Solutions with Short or Long Reads
Bulk or scATAC-Seq
Analyze chromatin accessibility across large cell populations
ChIP-Seq
Map protein-DNA interactions and histone modifications
Methylome Sequencing
Analyze DNA methylation patterns across the genome
Microbial Sequencing Solutions
Metagenomics Sequencing
Analyze the genetic content of microbial communities
16s rRNA Sequencing
Identify and classify bacteria in a sample
Microbial Genome Assembly
Reconstruct the complete genome sequences of individual microorganisms
Proteomic Solutions
Biomarker Discovery
Identify and quantify proteins biomarkers in biological samples
Immune Monitoring
Analyzing cytokine and inflammation-related proteins to track immune system activity or adverse effects
Target Identification
Validate causal proteins for diseases via proteogenomic studies
Real Solutions for Real-World Applications
Signios Bio offers specialized multiomics solutions designed to investigate the complexities of oncology, immunology, neurology, and rare & infectious diseases. By combining multiple modalities with our advanced bioinformatics, we are able to offer customized multiomics solutions for your research.
TME Signal
Identifies distinct cell populations and gene regulatory networks driving tumor evolution via transcriptomics at single-cell and spatial resolution
TCR/BCR Profile Signal
Investigates clonal expansion of antigen specific T and B cells via transcriptomics at single-cell resolution.
Neuroregulation Signal
Detects changes in methylation, chromatin structure, & identifies vulnerable neuronal populations using transcriptomics & epigenomics at single-cell and spatial resolution.
Precision DNA Signal
Catalogs genomic rearrangements, assembles uncharacterized regions, and classifies cellular targets via long read DNA sequencing.
Multi-level RNA Signal
Detects full-length RNA isoforms and resolves SVs via long read RNA sequencing.
Immunogenomic Signal
Maps chromatin accessibility changes and epigenetic features of memory immune cells at single-cell resolution.
Neuroimmune Signal
Establishes disease-associated neural cell populations and maps immune cell infiltration in the brain via spatial transcriptomics & epigenomics.
Pathogen Signal
Determines resistance genes, resolves complex genomes, and detects bacterial epigenetic regulation via long read DNA and methylation profiling.
Proven Impact
Elucidating biological pathways altered by traumatic brain injury and targets for therapeutic intervention
Our team collaborated with researchers at Virginia Tech to investigate the complex molecular mechanisms of traumatic brain injury (TBI) and associated alterations in gene expression. The study used single-cell and spatial transcriptomics to identify transcriptome-level changes and revealed potential new biological targets for therapeutic intervention.
Resources
April 2025
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Services Brochure
Precision NGS data, fast turnaround, insightful bioinformatics: complete solutions for every sample type
April 2025
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Services Brochure
Unlocking biological insights with Signios Bio’s advanced multiomics solutions
November 2024
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Blog Post
Exploring the new Human Cell Atlas release and its impact on genomic research